A systematic review of 32 randomized trials found positive effects on testosterone for ashwagandha and fenugreek extracts, but only 9 of the 32 trials showed significant increases and only 6 were low risk of bias. A 2026 meta-analysis put ashwagandha's average rise in men at about 57 ng/dL. That is real but modest.
What the research found
A 2021 systematic review in Advances in Nutrition examined 32 randomized controlled trials of single herbal ingredients and testosterone in men.
- Nine of the 32 trials reported statistically significant increases in testosterone.
- The review concluded that fenugreek seed extracts and ashwagandha root and root/leaf extracts had positive effects. It found some evidence for Asian red ginseng and forskohlii root extract.
- Only six of the 32 trials were judged to be low risk of bias, and half of them enrolled men under 40.
A 2026 meta-analysis of ashwagandha trials, published in Planta Medica, pooled 23 trials with 1,706 participants. It found ashwagandha increased testosterone in men, with a mean difference of about 57 ng/dL, but not in women. It also found lower cortisol.
Putting 57 ng/dL in context
The AUA guideline uses 300 ng/dL as a reasonable cutoff for low testosterone. A rise of around 57 ng/dL on average is real but modest. It is unlikely to turn a clinically low level into a normal one, and it does not tell you how any individual man will respond.
Limits and safety
- Trial quality is mixed. Many trials are small and short, and quality varies across studies.
- Products vary. Supplements are not approved by the FDA before they are sold. Look for standardized extracts and independent testing by USP, NSF, or Informed Choice.
- Safety. Case reports of liver injury have been described with ashwagandha. Check with a clinician first, especially if you have liver or thyroid conditions or take regular medications.
What to do with this
- Get the basics right first: sleep and, if relevant, weight loss.
- If you want to try a supplement, discuss it with a clinician and choose a third-party tested product.
- If you have symptoms of low testosterone, get tested rather than self-treating.
Sources
- Smith SJ, Lopresti AL, Teo SYM, Fairchild TJ. Examining the effects of herbs on testosterone concentrations in men: a systematic review. Adv Nutr 2021;12(3):744-765
- Hormonal modulation with Withania somnifera: systematic review and meta-analysis of randomized-controlled trials. Planta Med 2026;92(8):790-805
- Mulhall JP, et al. Evaluation and management of testosterone deficiency: AUA guideline (300 ng/dL cutoff)
This article is general education, not medical advice. Talk to a clinician about testing and treatment. Medical disclaimer.